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Updated: Aug 23, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 28, 2007
[Physiopathological and clinical aspects of Parkinson disease. Current problems]
Abstract:
Some interpretative hypotheses of the most important symptoms of Parkinson's disease are formulated, on the ground of acquired neurohistopathologic elements and in the light of new observations of experimental neuro-physiology. The possible role of the inferior olivary body in the genesis of parkinsonian tremor is pointed out. The psycho-behavioural disorders and among these the severe weakness of pulsional control and the scanty elaboration of the affective-emotional motivation would be in relation, according to the Authors, to the involvement of the pallido-habenular pathways and the habenuloreticular midbrain outflow (limbic midbrain area).
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