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Layered Double Hydroxides: Recent Progress and Promising Perspectives Toward Biomedical Applications.

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Layered double hydroxides (LDHs) show great promise for biomedical uses, including drug delivery and diagnostics. However, their clinical translation is limited, highlighting the need to address current research challenges.

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Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Nanotechnology

Background:

  • Layered double hydroxides (LDHs) possess advantageous properties like biocompatibility, degradability, and high loading capacity.
  • Their tunable structure and surface modification capabilities enable tailored applications.

Purpose of the Study:

  • To comprehensively review recent advances in LDH applications for biomedicine.
  • To identify challenges and limitations hindering clinical translation of LDHs.
  • To provide an outlook for future research directions.

Main Methods:

  • Literature review of recent advancements in LDH-based biomedical applications.
  • Analysis of current limitations and requirements for clinical translation.
  • Discussion of future research perspectives.

Main Results:

  • LDHs are versatile nanomaterials with potential in drug delivery, cancer therapy, tissue engineering, coatings, membranes, and biosensors.
  • Significant potential exists for LDHs in various biomedical fields.
  • Clinical translation of LDHs remains limited.

Conclusions:

  • LDHs offer substantial promise for diverse biomedical applications.
  • Addressing current limitations is crucial for advancing LDH clinical translation.
  • Future research should focus on overcoming barriers to clinical implementation.