Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

RNA-DNA Fusomer Fibers With Customizable Physicochemical, Mechanical, and Biological Properties for Next-Generation Therapeutics.

Small (Weinheim an der Bergstrasse, Germany)·2026

Same author

Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026

Same author

When small gets smart: how the application of nanotechnology is transforming immunology in the 21<sup>st</sup> Century.

Nanomedicine (London, England)·2026

Same author

Comparative analyses for plant virus-based cancer immunotherapy drug development.

Cell biomaterials·2026

Same author

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral-Like Immunomodulatory Responses and Potent Adjuvant Activity.

Advanced functional materials·2026

Same author

Structure-function relationship of S protein cleavage in cowpea mosaic virus intratumoral immunotherapy.

Biomaterials science·2025

Search research articles

Related Experiment Video

Updated: Jun 30, 2025

Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection

Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection

Published on: September 1, 2023

Analysis of Nanoparticle Adjuvant Properties.

Barry W Neun¹, Edward Cedrone¹, Marina A Dobrovolskaia²

¹Nanotechnology Characterization Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.

Methods in Molecular Biology (Clifton, N.J.)

|March 20, 2024

Summary

This study outlines how to design animal studies to test if engineered nanomaterials can act as adjuvants, enhancing vaccine effectiveness by improving antigen delivery and immune response.

Keywords:

Adjuvant Antibody Antigen Nanoparticles Vaccines

More Related Videos

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization

Published on: September 2, 2022

Author Spotlight: Development and Evaluation of a Cationic Nanoemulsion-Encapsulated Retinoic Acid System for Mucosal Vaccination

Author Spotlight: Development and Evaluation of a Cationic Nanoemulsion-Encapsulated Retinoic Acid System for Mucosal Vaccination

Published on: February 23, 2024

Related Experiment Videos

Last Updated: Jun 30, 2025

Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection

Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection

Published on: September 1, 2023

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization

Published on: September 2, 2022

Author Spotlight: Development and Evaluation of a Cationic Nanoemulsion-Encapsulated Retinoic Acid System for Mucosal Vaccination

Author Spotlight: Development and Evaluation of a Cationic Nanoemulsion-Encapsulated Retinoic Acid System for Mucosal Vaccination

Published on: February 23, 2024

Area of Science:

Immunology
Nanotechnology
Vaccinology

Background:

Nanoparticles are utilized in vaccine development for targeted antigen delivery to immune cells, enhancing immunogenicity.
Nanotechnology platforms, initially for drug delivery, may possess inherent immunomodulatory functions beneficial for vaccine efficacy.

Purpose of the Study:

To describe an experimental approach for designing in vivo animal studies.
To verify the adjuvant properties of engineered nanomaterials for improving vaccine efficacy.

Main Methods:

Designing animal study protocols.
In vivo proof-of-concept studies.
Evaluating nanocarrier utility for vaccine enhancement.

Main Results:

The study provides a framework for assessing nanocarrier adjuvant properties.
The described approach is crucial for validating nanotechnology in vaccine development.

Conclusions:

An in vivo proof of concept study is essential to confirm nanocarrier utility for vaccine efficacy.
This work guides the design of studies to test nanomaterial adjuvant properties in vivo.