Related Experiment Video
Updated: May 7, 2026

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Animal models of eosinophilic esophagitis
Jennifer M Pilat1, Justin Jacobse1,2,3,4, Matthew A Buendia5
1Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, 1075 Medical Research Building IV, B-2215 Garland Ave, Nashville, TN 37232, United States.
Abstract:
Eosinophilic esophagitis is a chronic inflammatory disorder of the esophagus. Over the past 25 yr, great strides have been made toward understanding its pathogenesis, in part due to studies in several types of animal models. The vast majority of these models have been characterized in mice. In this review, we summarize the histopathological features of eosinophilic esophagitis recapitulated by these animal models, as well as discuss their strengths and weaknesses.

