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Updated: Jun 30, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
The Use of Proton and Carbon Ion Radiation Therapy for Sarcomas
Myrsini Ioakeim-Ioannidou1, Melanie Rose2, Yen-Lin Chen1
1Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA.
Abstract:
The unique physical and biological characteristics of proton and carbon ions allow for improved sparing of normal tissues, decreased integral dose to the body, and increased biological effect through high linear energy transfer. These properties are particularly useful for sarcomas given their histology, wide array of locations, and age of diagnosis. This review summarizes the literature and describes the clinical situations in which these heavy particles have advantages for treating sarcomas.
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