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Optical method supported by machine learning for dynamics of C-reactive protein concentrations changes detection in
Patryk Sokołowski1, Kacper Cierpiak1, Małgorzata Szczerska1
1Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdańsk University of Technology, Gdańsk, Poland.
Journal of Biophotonics
|March 20, 2024
Summary
This study introduces a new spectroscopy and machine learning method for rapid wastewater detection of infectious agents. This approach aids in early epidemic detection and reduces costly, time-consuming traditional methods.
Area of Science:
- Environmental science
- Biotechnology
- Analytical chemistry
Background:
- Wastewater monitoring is crucial for public health surveillance, especially during epidemics.
- Early detection of infectious agents and inflammation biomarkers in communities is vital.
- Current detection methods are often time-consuming and costly.
Purpose of the Study:
- To develop a novel spectroscopy method enhanced with machine learning for real-time detection of infectious agents in wastewater.
- To enable rapid screening of inflammatory conditions and infectious diseases in community settings.
- To reduce the time and cost associated with traditional infectious disease detection.
Main Methods:
- Utilized spectroscopy in the 220-750 nm range.
- Employed machine learning algorithms for data analysis and prediction.
- Integrated absorption spectrophotometry with machine learning for detection.
Main Results:
- Achieved up to 68% accuracy in prediction models.
- Demonstrated the potential for real-time detection of infectious agents.
- Showcased the universality of the method with various detectors.
Conclusions:
- The novel spectroscopy and machine learning method offers a promising approach for real-time wastewater-based epidemiology.
- This technique can significantly improve the speed and efficiency of infectious disease surveillance.
- The method's adaptability with different detectors enhances its potential for widespread application.

