[Ischemic stroke in men 18-50 years of age]
1Yaroslavl State Medical University, Yaroslavl, Russia.
Insights
This study identified key modifiable risk factors for ischemic stroke (IS) in young men. Arterial hypertension, dyslipidemia, and smoking were prevalent across IS subtypes.
Area of Science:
- Neurology
- Cardiovascular Medicine
Context:
- Ischemic stroke (IS) affects men aged 18-50, with varying subtypes.
- Understanding modifiable risk factors is crucial for targeted prevention.
Purpose:
- To evaluate modifiable risk factors for ischemic stroke (IS) in men aged 18-50.
- To analyze the characteristics of atherothrombotic, cardioembolic, and lacunar IS subtypes in this demographic.
Summary:
- The study analyzed 125 men with IS, identifying atherothrombotic (60), lacunar (46), and cardioembolic (19) subtypes.
- Major risk factors included hypertension (83.2%), smoking (67.2%), and dyslipidemia (50.4%).
- Risk factor prevalence varied by IS subtype and patient age.
Impact:
- Provides insights into the primary modifiable risk factors for IS in young men.
- Highlights differences in risk factor profiles across IS subtypes.
- Informs clinical practice and public health strategies for stroke prevention in younger populations.
Objective:
To evaluate the main modifiable risk factors for ischemic stroke (IS) and features of the course in atherothrombotic, cardioembolic, and lacunar subtypes of IS in men aged 18-50 years.
Material And Methods:
The study included 125 men (the mean age was 42.6±5.3 years) who were admitted to the Vascular department before the COVID-19 pandemic and survived for the first 30 days after IS. Information on patients' baseline characteristics, traditional vascular risk factors, and lifestyle risk factors was systematically collected. Neuroimaging, ultrasound and laboratory tests were performed.
Results:
Atherothrombotic subtype was identified in 60 patients, lacunar subtype in 46 patients and cardioembolic subtype in 19 patients. In the group as a whole, major risk factors included arterial hypertension (83.2%), dyslipidemia (50.4%), smoking (67.2%), alcohol consumption (29.6%), obesity (16.8%), heart rhythm disorders (12%), and diabetes mellitus (8%).
Conclusion:
The study revealed the main risk factors, the frequency of which differed depending on the stroke subtype and the age of the patients.
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