[Features of primary and recurrent ischemic stroke in men aged 18-50 years]
N A Pizov1, M V Bakucheva1, O P Rechkina2
1Clinical Hospital No. 2, Yaroslavl, Russia.
Insights
This study analyzed primary and recurrent ischemic stroke in young men, revealing distinct risk factor profiles and physiological differences between stroke types and subtypes. Understanding these features is crucial for targeted prevention and treatment strategies.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Vascular Biology
Objective:
To evaluate the features of primary and recurrent stroke in men aged 18-50 years with atherothrombotic, lacunar, and cardioembolic subtypes.
Material And Methods:
A total of 125 men with primary and recurrent stroke were included in the study. The main vascular risk factors and lifestyle-related risk factors were assessed. Neurological, neuroimaging, ultrasound and laboratory examinations were performed. Hemostasis parameters, lipid metabolism and endothelial function parameters were studied.
Results:
Among 125 men with ischemic stroke with a median age of 43 years, 104 (83.2%) patients had a primary stroke and 21 (16.8%) patients had a recurrent stroke. Recurrent stroke occurred more frequently in patients with the cardioembolic subtype (26.3%) and with almost equal frequency in patients with the atherothrombotic (13.3%) and lacunar (17.4%) subtypes. In the group as a whole, patients with primary and recurrent strokes did not differ in age (43.1±5.5 and 43.7±4.3 years, respectively). In a comparative analysis of patients with primary and recurrent stroke with different subtypes of stroke, significant differences in the main risk factors, indicators of lipid metabolism, hemostasis and endothelial function were obtained.
Conclusion:
The study in men, aged 18-50 years, with atherothrombotic, lacunar and cardioembolic subtypes revealed the features of risk factors, indicators of hemostasis system, lipid metabolism and endothelial function in primary and recurrent stroke.
