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Published on: October 1, 2015
[HCV antigen detection method and clinical application]
1Shangdong Institute of Industrial Technology for Health Sciences and Precision Medicine, Jinan 250100, China.
Insights
Hepatitis C virus (HCV) antigen detection offers earlier diagnosis than antibody tests. This review covers new HCV antigen methods for improved early detection and treatment strategies.
Area of Science:
- Hepatology
- Virology
- Clinical Diagnostics
Background:
- Hepatitis C virus (HCV) infection is a global health concern.
- Current diagnostics rely on anti-HCV antibody and HCV RNA detection.
- A significant diagnostic window period exists with traditional methods.
Conclusions:
- HCV antigen detection represents a significant improvement for early diagnosis.
- Implementing advanced antigen detection strategies can enhance patient outcomes.
- Further research into optimized HCV antigen testing protocols is warranted.
Abstract:
Hepatitis C is distributed worldwide and possesses a hidden characteristic. The traditional methods of screening and diagnosis of hepatitis C infection commonly used in clinics are based on anti-HCV antibody and HCV RNA detection. Advances in HCV antigen detection technologies can apparently reduce the window period for anti-HCV antibodies, providing new clinical evidence for the early detection, diagnosis, and treatment of HCV infection. This article is a current review of HCV antigen detection methodologies, clinical applications, and detection strategies.
