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Updated: Jun 30, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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GAS41 modulates ferroptosis by anchoring NRF2 on chromatin

Zhe Wang1, Xin Yang1, Delin Chen1

  • 1Institute for Cancer Genetics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.

Nature Communications
|March 22, 2024
PubMed
Summary

GAS41 protein represses ferroptosis by anchoring the transcription factor NRF2 to target genes like SLC7A11. This mechanism, involving histone markers, highlights GAS41

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