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Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography
Published on: May 15, 2017
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Non-steady state thermometry with optical diffraction tomography
Adarsh B Vasista1, Bernard Ciraulo1,2, Falko Schmidt1
1Nanophotonic Systems Laboratory, Department of Mechanical and Process Engineering, ETH-Zürich, 8092 Zürich, Switzerland.
Science Advances
|March 22, 2024
Summary
This study introduces pump-probe optical diffraction tomography (ODT) for 3D temperature mapping at the single-particle level. This advanced label-free thermometry method overcomes limitations of existing techniques, enabling analysis of complex heat sources.
Area of Science:
- Nanoscale science
- Optical physics
- Thermodynamics
Background:
- Label-free thermometry is crucial but limited to planar, steady-state heat sources.
- Current methods restrict the study of complex thermal landscapes.
- Single-particle thermal analysis is often challenging.
Purpose of the Study:
- To develop and validate a novel 3D label-free thermometry technique.
- To enable precise temperature mapping of nonplanar heat sources and diffusing nanoparticles.
- To extend the capabilities of thermal analysis in complex microenvironments.
Main Methods:
- Utilized pump-probe optical diffraction tomography (ODT) for thermal mapping.
- Systematically characterized thermal landscapes in gold nanorod microchamber models.
- Benchmarked ODT results against simulations and quantitative phase imaging thermometry.
Main Results:
- Demonstrated accurate and precise 3D temperature mapping at the single-particle level.
- Successfully resolved thermal landscapes of nonplanar heat sources.
- Applied ODT thermometry to freely diffusing gold nanorods in microchambers.
Conclusions:
- ODT thermometry offers a powerful new tool for label-free thermal analysis.
- The method overcomes limitations of traditional thermometry for complex systems.
- This technique is expected to advance studies requiring 3D or non-steady-state thermal characterization of nanoparticles.
