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Related Experiment Video

Updated: Jun 30, 2025

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography
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Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

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Non-steady state thermometry with optical diffraction tomography.

Adarsh B Vasista1, Bernard Ciraulo1,2, Falko Schmidt1

  • 1Nanophotonic Systems Laboratory, Department of Mechanical and Process Engineering, ETH-Zürich, 8092 Zürich, Switzerland.

Science Advances
|March 22, 2024
PubMed
Summary
This summary is machine-generated.

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This study introduces pump-probe optical diffraction tomography (ODT) for 3D temperature mapping at the single-particle level. This advanced label-free thermometry method overcomes limitations of existing techniques, enabling analysis of complex heat sources.

Area of Science:

  • Nanoscale science
  • Optical physics
  • Thermodynamics

Background:

  • Label-free thermometry is crucial but limited to planar, steady-state heat sources.
  • Current methods restrict the study of complex thermal landscapes.
  • Single-particle thermal analysis is often challenging.

Purpose of the Study:

  • To develop and validate a novel 3D label-free thermometry technique.
  • To enable precise temperature mapping of nonplanar heat sources and diffusing nanoparticles.
  • To extend the capabilities of thermal analysis in complex microenvironments.

Main Methods:

  • Utilized pump-probe optical diffraction tomography (ODT) for thermal mapping.
  • Systematically characterized thermal landscapes in gold nanorod microchamber models.

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Last Updated: Jun 30, 2025

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  • Benchmarked ODT results against simulations and quantitative phase imaging thermometry.
  • Main Results:

    • Demonstrated accurate and precise 3D temperature mapping at the single-particle level.
    • Successfully resolved thermal landscapes of nonplanar heat sources.
    • Applied ODT thermometry to freely diffusing gold nanorods in microchambers.

    Conclusions:

    • ODT thermometry offers a powerful new tool for label-free thermal analysis.
    • The method overcomes limitations of traditional thermometry for complex systems.
    • This technique is expected to advance studies requiring 3D or non-steady-state thermal characterization of nanoparticles.