Related Experiment Video
Updated: Jun 30, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Improved Screening for Depression in Patients Initiating Fertility Treatment
Objective:
To improve screening for depression in patients who are initiating fertility treatment at a reproductive endocrinology and infertility (REI) center by screening all patients at their initial visit using the Patient Health Questionnaire-9 (PHQ-9).
Design:
This quality improvement project was conducted using a plan-do-study-act cycle implemented with a postintervention study design.
Setting/Local Problem:
A medium-size REI center in a mid-Atlantic U.S. metropolitan area where screening for mental health status in patients initiating fertility treatments was not occurring.
Participants:
Patients who were scheduled in person with REI providers for a new patient consult regarding fertility were declared eligible.
Intervention/Measurements:
The PHQ-9 was administered by providers at initial consults for patients seeking fertility treatments from October 2022 to February 2023. Three cycles of the plan-do-study-act model were used to execute change. For all patients who scored 5 to 9 (mild depression), conversations regarding counseling referrals occurred. For all patients who scored ≥10 (moderate to severe depression), a referral for counseling and medication management was generated. Data were analyzed via descriptive statistics.
Results:
A total of 115 participants were included. A screening rate of 84.3% (n = 97) was achieved for patients initiating treatment. Of the 97 screened, 21 patients had a score of ≥5; 19 were given a referral for counseling. However, none of the patients attended a counseling session or started medication prescribed by their primary care provider during the 2-month follow-up period. Barriers identified included costs, personal preferences, and access to services.
Conclusion:
The PHQ-9 screening tool was implemented at an REI clinic to improve the frequency of mental health screenings and provide necessary referrals. However, additional follow-up is needed to ensure patients are receiving appropriate mental health care.
Related Concept Videos
Antidepressant Drugs: MAOIs and Other Agents
Depression: Overview
Infertility in Males
In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of...

