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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Bone Marrow Sampling and Transplants01:22

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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The ABO Blood Group01:12

The ABO Blood Group

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The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
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Updated: Jun 30, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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Examining Injustices: Transfusion Medicine and Race.

Sumedha Arya1, Alyson Mahar2, Jeannie Callum3

  • 1Canadian Blood Services, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Transfusion Medicine Reviews
|March 22, 2024
PubMed
Summary
This summary is machine-generated.

Race and ethnicity are social constructs, not biological. This review critically assesses transfusion medicine studies, highlighting disparities and methodological challenges to promote race-conscious healthcare.

Keywords:
Health equityRacismReviewTransfusion medicine

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Area of Science:

  • Transfusion Medicine
  • Health Equity
  • Sociology of Science

Background:

  • Race and ethnicity are sociopolitical constructs, not biological realities.
  • Previous assertions of biological meaning in these descriptors have caused significant harm.
  • Critical assessment of transfusion medicine literature is crucial for advancing race-conscious medicine.

Purpose of the Study:

  • To critically appraise transfusion medicine studies examining race and healthcare disparities.
  • To identify and analyze methodological challenges within this research area.
  • To inform the responsible use of race and ethnicity in medical research.

Main Methods:

  • Literature review and critical appraisal of transfusion medicine studies.
  • Application of current definitions and health equity frameworks.
  • Focus on methodological challenges and disparities at the intersection of race and healthcare.

Main Results:

  • Identified significant methodological challenges in transfusion medicine research involving race and ethnicity.
  • Highlighted how race-based approaches can perpetuate healthcare disparities.
  • Emphasized the need for a shift towards race-conscious medical practices.

Conclusions:

  • Transfusion medicine research must address the sociopolitical nature of race and ethnicity.
  • Future research requires risk modeling that incorporates upstream factors and patient input.
  • Development of expert consensus and adherence to reporting guidelines are essential for critical evaluation of this literature.