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Updated: Jun 29, 2025

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
Living Cell as a Self-Synchronized Chemical Reactor
Robert Hołyst1, Grzegorz Bubak1, Tomasz Kalwarczyk1
1Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Abstract:
Thermal fluctuations power all processes inside living cells. Therefore, these processes are inherently random. However, myriad multistep chemical reactions act in concerto inside a cell, finally leading to this chemical reactor's self-replication. We speculate that an underlying mechanism in nature must exist that allows all of these reactions to synchronize at multiple time and length scales, overcoming in this way the random nature of any single process in a cell. This Perspective discusses what type of research is needed to understand this undiscovered synchronization law.

