Related Experiment Video
Updated: Jun 29, 2025

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
Utilizing Pharmacogenomics Results to Improve Statin-Associated Muscle Symptoms
Coral Perez González1, Chandni Bardolia1, Katie Pizzolato1
11 Office of Translational Research and Residency Programs, Tabula Rasa HealthCare, Moorestown, New Jersey.
Abstract:
The objective of this aims to demonstrate the advantage of a pharmacogenomics (PGx)-informed medication review in mitigating adverse drug events (ADEs) and optimizing therapeutic outcomes. PGx testing and PGx-informed medication reviews assist in mitigating ADEs. PGx testing was performed on a 68-year-old male presenting with uncontrolled chronic pain. The PGx results highlighted a drug-gene interaction, aiding in identification of the increased risk of statin-associated muscle symptoms (SAMS) attributing to uncontrolled chronic pain. This patient case report illustrates how incorporating PGx results can help improve chronic pain and mitigate ADEs, such as SAMS.
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