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Congenital Heart Defects in Pregnancies Conceived by Assisted Reproductive Technology: Comparing Functional and
Saeid Rasouli1, Mohammad Radgoodarzi2, Reza Azarbad1
1Pediatrics, Iran University of Medical Sciences, Tehran, IRN.
Cureus
|March 26, 2024
Summary
This study found no increased risk of congenital heart defects (CHD) in pregnancies conceived via assisted reproductive technology (ART). Specialized echocardiography is not deemed necessary for ART-conceived fetuses.
Area of Science:
- Cardiology
- Reproductive Medicine
- Fetal Medicine
Background:
- Congenital heart defects (CHD) are common anomalies, with a debated association with assisted reproductive technology (ART).
- Evaluating the necessity of specialized fetal echocardiography in ART pregnancies is crucial.
Purpose of the Study:
- To assess the association between ART and CHD.
- To determine the need for specialized echocardiography in ART pregnancies.
Main Methods:
- Retrospective study of 109 pregnancies (56 ART, 53 non-ART) in Tehran, Iran.
- Two-dimensional and color Doppler fetal echocardiography performed.
- Medical records reviewed for structural and functional heart defects.
Main Results:
- No significant difference in structural heart defects (ASD, VSD) between ART and non-ART groups (P=0.58).
- No significant difference in cardiac rhythm (P=0.51).
- TR-PG index showed a statistical difference (P=0.02), but overall cardiac function was not impaired.
Conclusions:
- No association found between ART and congenital heart defects.
- ART fetuses did not exhibit heart dysfunction.
- Specialized echocardiography by pediatric cardiologists is not necessary for ART-conceived fetuses.
