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Updated: Jun 21, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Heterotopic Ossification of the Abdomen: A Rare Sequela Following Trauma and Damage Control Laparotomy
Patrick Cherfan1,2, Michael D Cobler-Lichter1,2, Joshua P Kronenfeld1,2
1Division of Trauma, Surgical Critical Care & Burns, Dewitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Abstract:
Heterotopic ossification (HO) of the abdomen is a rare yet highly morbid complication following blunt and penetrating trauma requiring damage control laparotomy. We present the case of a 22-year-old man, 20 months after life-threatening motor vehicle crash with major vascular injury requiring multiple abdominal surgeries. The patient was initially treated at a community hospital and subsequently developed a chronic left lower quadrant enterocutaneous fistula, accompanied by a gradually worsening diffuse abdominal pain. He was referred to our tertiary care center with extensive skin breakdown and an inability to control the fistula despite numerous wound care consultations. He also had severe abdominal deformities due to HO in the abdominal wall, peritoneum, paraspinal muscles, and parapelvic regions. As HO is largely underreported, it is crucial to refer those patients, once medically stabilized, to tertiary care centers for surveillance and possible treatment when symptomatic.
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