Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

Renewal of Skin Epidermal Stem Cells

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

High-ratio plasma resuscitation decreases mortality in moderate traumatic brain injury.

The journal of trauma and acute care surgery·2026

Same author

Trauma Training for Emergency Department Physicians in Low- and Middle-Income Countries: A Scoping Review.

AEM education and training·2026

Same author

Female patients receiving massive transfusion are less likely to receive whole blood despite survival benefit.

The journal of trauma and acute care surgery·2026

Same author

Therapeutic role of mesenchymal stem cells in second-degree burn wound repair: Integration with split-thickness skin grafts.

Scars, burns & healing·2025

Same author

Association of Trainee Gender With Critically-Ill Trauma Patient Outcomes.

The Journal of surgical research·2025

Same author

Marijuana Use in a Nationwide Survey of Burn Survivors.

Journal of burn care & research : official publication of the American Burn Association·2025

Same journal

Challenges in Antimicrobial Treatment and Antimicrobial Stewardship in Hospital-Acquired Infections in Adult Burn Patients.

European burn journal·2026

Same journal

Bridging the Evidence-Practice Gap in Early Burn Injury Care: A Comprehensive Evidence Synthesis of Global Guidelines, Consensus, and Systematic Reviews for Resource-Limited Settings.

European burn journal·2026

Same journal

Automated Classification of Second- and Third-Degree Burn Images Using Convolutional Neural Networks.

European burn journal·2026

Same journal

A Single-Centre Review of Outcomes of Delayed Admission to a Burns Unit.

European burn journal·2026

Same journal

The 4th Educational Course of the European Burns Association (EBA).

European burn journal·2026

Same journal

Japanese Consensus Document on NexoBrid<sup>®</sup>, a Burn Eschar Removal Agent.

European burn journal·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 28, 2026

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

Published on: June 29, 2022

Simulation Enhances Resident Preparedness Using Skin Cell Suspension Autograft.

Joshua P Kronenfeld¹, Louis R Pizano¹, Ray I Gonzalez¹

¹Division of Trauma, Surgical Critical Care & Burns, Daughtry Family Department of Surgery, University of Miami Miller School of Medicine and Jackson Memorial Hospital Ryder Trauma Center, Miami, FL 33136, USA.

European Burn Journal

|May 27, 2026

Summary

This summary is machine-generated.

Simulation training for skin cell suspension autograft (SCSA) significantly boosted surgical residents' confidence and performance. This novel approach promises faster mastery and improved operative efficiency for new surgical techniques.

Keywords:

burns residency simulation surgery training

More Related Videos

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Published on: March 4, 2016

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Related Experiment Videos

Last Updated: May 28, 2026

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

Published on: June 29, 2022

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Published on: March 4, 2016

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Published on: February 24, 2016

Area of Science:

Medical Education
Surgical Training
Regenerative Medicine

Background:

Surgical simulation enhances skill acquisition for complex procedures.
Simulation training is often overlooked for new device implementation.
Burn surgery rotations present opportunities for novel training methods.

Purpose of the Study:

To design and evaluate a simulation training program for the skin cell suspension autograft (SCSA).
To assess the impact of SCSA simulation on surgery residents during their Burn rotation.

Main Methods:

Residents engaged with instructional materials and videos prior to a supervised simulation lab session.
A qualitative survey was administered post-rotation to gather feedback.

Main Results:

Twelve residents completed the SCSA simulation training.
Feedback indicated the simulation was well-paced (4.6/5.0), thorough (4.8/5.0), and increased confidence (4.4/5.0) while reducing apprehension (4.4/5.0).
Residents successfully utilized the SCSA product in operating room procedures post-training.

Conclusions:

The SCSA simulation training demonstrates significant potential for enhancing surgical resident confidence and procedural performance.
This training may expedite resident independence, improve operative efficiency, and elevate trainee expertise.