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Author Spotlight: RNA FISH for Locating lncRNA-SNHG6 in Osteosarcoma Cells
Published on: June 16, 2023
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Intelligent structure prediction and visualization analysis of non-coding RNA in osteosarcoma research
Longhao Chen1,2, Liuji He3, Baijie Liu3
1The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Frontiers in Oncology
|March 27, 2024
Summary
This bibliometric analysis maps the research landscape of non-coding RNAs (ncRNAs) in osteosarcoma (OS). It identifies key contributors, emerging trends like the tumor microenvironment, and future research directions for ncRNA in OS.
Area of Science:
- Bibliometrics and knowledge structure analysis
- Oncology and molecular biology
- Non-coding RNA research
Background:
- Osteosarcoma (OS) is a prevalent bone cancer in children and adolescents.
- Non-coding RNAs (ncRNAs) play a crucial role in OS development.
- A comprehensive bibliometric analysis of ncRNAs in OS research is lacking.
Approach:
- Bibliometric analysis of 3,642 papers on ncRNAs in OS (2001-2023) from the Web of Science Core Collection.
- Utilized VOSviewers, CiteSpace, and Pajek for data analysis.
- Examined publication trends, country/institution contributions, author networks, and keyword co-occurrence.
Key Points:
- China leads in publications; Nanjing Medical University and Shanghai Jiao Tong University are top institutions.
- Key ncRNA types include miRNA, lncRNA, and circRNA, focusing on migration, invasion, apoptosis, proliferation, prognosis, biomarkers, and chemoresistance.
- Recent trends highlight the tumor microenvironment, immune interactions, and exosomes in OS ncRNA research.
Conclusions:
- This study provides the first comprehensive bibliometric overview of ncRNAs in OS.
- Identifies current research hotspots and emerging trends.
- Offers insights for future research directions in ncRNA-based OS studies.
