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Anders Bonde Jensen1,2, Peer Christiansen1,3, Pernille Bech1,3

  • 1Danish Breast Cancer Group Centre for Late Effects, Aarhus Universitetshospital.

Ugeskrift for Laeger
|March 27, 2024
PubMed
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Breast cancer survivors face long-term side effects from treatment, impacting quality of life. Further research is needed on risk factors and effective management strategies for these late effects.

Area of Science:

  • Oncology
  • Survivorship Care

Background:

  • Improved breast cancer survival rates increase the incidence of treatment-related late effects.
  • These late effects significantly impact survivors' quality of life.

Approach:

  • This review summarizes key late effects following breast cancer treatment.
  • Categorizes late effects into those from locoregional, systemic, and general treatments.

Key Points:

  • Locoregional treatment can cause lymphedema, shoulder dysfunction, and pain.
  • Systemic therapies may lead to polyneuropathy, premature menopause, and cardiovascular issues.
  • General late effects include fatigue, insomnia, and cognitive impairment.

Conclusions:

  • There is a critical need for enhanced understanding of risk factors, prognoses, and optimal treatments for cancer-related late effects.

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  • Further research is essential to improve long-term survivorship care and patient outcomes.