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Association between the American Heart Association's new "Life's Essential 8" metrics and kidney stone

Xingmo Dong1, Lihua Liao1,2, Yani Wang1,2

  • 1Longyan First Affiliated Hospital of Fujian Medical University, Longyan, 364000, China.

World Journal of Urology
|March 27, 2024
PubMed

Insights

Maintaining ideal cardiovascular health (CVH) is linked to a lower risk of developing kidney stones. This finding highlights the importance of a healthy lifestyle for preventing kidney stone disease.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Kidney stone disease incidence is rising globally, imposing significant medical and social costs.
  • Cardiovascular diseases (CVDs) share risk factors with kidney stones, suggesting a potential link.

Purpose of the Study:

  • To investigate the association between cardiovascular health (CVH), assessed by the American Heart Association's Life's Essential 8 (LE8) score, and the incidence of kidney stone disease.
  • To determine if better CVH correlates with a reduced risk of kidney stone formation.

Main Methods:

  • Analysis of 29,469 US adults from the National Health and Nutrition Examination Survey (2007-2018).
  • Categorization of participants into poor, intermediate, and ideal CVH groups based on LE8 scores.
  • Logistic regression models were employed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for kidney stone incidence across CVH categories.

Main Results:

  • Ideal CVH was significantly associated with reduced odds of kidney stone occurrence compared to poor CVH (adjusted OR: 0.45, 95% CI: 0.35-0.57).
  • Achieving 6 or more ideal CVH metrics further decreased the odds of kidney stone occurrence by up to 61% (adjusted OR: 0.39, 95% CI: 0.30-0.51).

Conclusions:

  • Ideal cardiovascular health, reflecting a healthy lifestyle, is inversely associated with the odds of developing kidney stone disease.
  • Promoting ideal CVH may be a strategy to mitigate the risk and burden of kidney stone disease.
Abstract

Keywords:
Cardiovascular healthKidney stoneLife’s Essential 8 (LE8)National Health and Nutrition Examination Survey (NHANES)

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