Significantly Elevated FDG Activity in Neurothekeoma

Area of Science:

• Oncology
• Radiology
• Dermatology

Background:

• Neurothekeoma is a rare, typically benign cutaneous neoplasm predominantly affecting young individuals.
• Diagnostic imaging plays a crucial role in the management of rare tumors.

Observation:

• A 16-year-old male presented with a primary neurothekeoma on his right shoulder.
• Positron Emission Tomography/Computed Tomography (PET/CT) imaging was performed.

Findings:

• Intense Fluorodeoxyglucose (FDG) uptake was observed at the site of the primary neurothekeoma.
• Two years post-diagnosis, the same patient exhibited abnormal FDG activity in metastatic neurothekeoma within the lung.

Implications:

• This case suggests that FDG PET/CT may be a valuable tool for detecting and monitoring neurothekeoma, including metastatic disease.
• Further research is warranted to explore the utility of FDG PET/CT in the broader clinical context of neurothekeoma management.