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Laser Therapy Effects on Periodontal Status: A Randomized Study Using Gaussian Network Analysis and Structural
Codruta Elena Ciurescu1, Lorena Dima1, Vlad Alexandru Ciurescu2
1Department of Fundamental Disciplines and Clinical Prevention, Faculty of Medicine Brasov, "Transylvania" University of Brasov, 56 Nicolae Balcescu Str., 500019 Brasov, Romania.
Medicina (Kaunas, Lithuania)
|March 28, 2024
Summary
Laser therapy combined with scaling and root planing significantly improves periodontal health. This approach reduces periodontal pocket depth and bleeding, enhancing clinical attachment levels for better treatment outcomes.
Area of Science:
- Periodontology
- Biomedical Engineering
- Computational Biology
Background:
- Periodontitis treatment traditionally involves scaling and root planing.
- Advanced modeling techniques like Gaussian graphical models (GGMs) and structural equations (SEM) offer new ways to analyze treatment efficacy.
Purpose of the Study:
- To evaluate the role of laser therapy in periodontitis treatment.
- To utilize computational prediction and advanced modeling for assessing treatment outcomes.
Main Methods:
- A randomized controlled trial with 40 patients with periodontitis (pocket depth ≥ 5 mm).
- Comparison between a control group (scaling, root planing, chlorhexidine) and a laser group (scaling, root planing, Er,Cr:YSGG laser).
- Measurement of periodontal pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), and plaque index (PI) over 4 years.
Main Results:
- Laser therapy addition to scaling and root planing resulted in decreased PPD and BOP.
- Significant improvements in clinical attachment level (CAL) were observed with laser therapy.
- Network analysis (GGMs) and SEM highlighted key relationships between periodontal indicators.
Conclusions:
- Laser therapy, when combined with conventional treatment, offers significant clinical benefits for periodontitis.
- GGMs and SEM are suitable for analyzing and confirming the success of periodontal interventions.
- The study confirms the efficacy of Er,Cr:YSGG laser in improving periodontal parameters.

