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Sacral Neuromodulation: Device Improvement and Current Applications in Urology.
Marco Spilotros1, Salvatore Gerbasi1, Francesco Lasorsa1
1Andrology and Kidney Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area-Urology, University of Bari "Aldo Moro", 70124 Bari, Italy.
Medicina (Kaunas, Lithuania)
|March 28, 2024
Summary
Sacral neuromodulation (SNM) treats overactive bladder and urinary retention when other methods fail. This therapy modulates spinal cord reflexes and brain networks for improved bladder control.
Area of Science:
- Urology
- Neurology
- Medical Devices
Background:
- Idiopathic overactive bladder (OAB) and non-obstructive urinary retention (NOR) affect patients unresponsive to conservative treatments.
- Sacral neuromodulation (SNM) provides a therapeutic option for refractory OAB and NOR.
- The precise mechanism of SNM involves modulating spinal cord reflexes and brain networks via peripheral afferents.
Purpose of the Study:
- To review the current applications and advancements in sacral neuromodulation for urological conditions.
- To highlight the efficacy of SNM in patients with overactive bladder and non-obstructing urinary retention.
- To discuss the evolving surgical techniques and device improvements in SNM therapy.
Main Methods:
- Percutaneous implantation of a quadripolar lead through the third sacral foramen (S3) under fluoroscopic guidance.
- Procedure performed under local or general anesthesia with patients in the prone position.
- Utilizes a two-stage implantation technique, a modern surgical approach.
Main Results:
- SNM is an effective treatment for patients with idiopathic OAB and NOR who have failed conservative therapies.
- Improvements in surgical techniques and device technology have expanded SNM applications.
- SNM is increasingly utilized for neurogenic lower urinary tract dysfunction.
Conclusions:
- Sacral neuromodulation is a valuable therapeutic option for various lower urinary tract dysfunctions.
- Advancements in SNM technology and surgical approaches enhance its clinical utility.
- SNM offers a viable solution for patients with refractory overactive bladder, urinary retention, and neurogenic bladder.

