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Updated: Jun 29, 2025

Doppler Optical Coherence Tomography of Retinal Circulation
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Optical Coherence Tomography Versus Optic Disc Photo Assessment in Glaucoma Screening.

Luiz Arthur F Beniz1, Veronica P Campos, Felipe A Medeiros

  • 1Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL.

Journal of Glaucoma
|March 28, 2024
PubMed
Summary

Optical coherence tomography (OCT) and optic disc photography offer distinct glaucoma screening benefits. Integrating artificial intelligence (AI) with objective OCT data shows promise for improving large-scale glaucoma detection accuracy.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Artificial Intelligence in Healthcare

Background:

  • Glaucoma screening is crucial for early detection and prevention of vision loss.
  • Optical coherence tomography (OCT) and optic disc photography are key diagnostic tools.
  • Each method has unique strengths and limitations impacting screening efficacy.

Purpose of the Study:

  • To review and compare the capabilities of OCT and optic disc photography for glaucoma screening.
  • To identify the limitations and challenges associated with each screening method.
  • To explore the potential of artificial intelligence (AI) in enhancing glaucoma screening.

Main Methods:

  • Comprehensive literature review on OCT and optic disc photography in glaucoma screening.

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Last Updated: Jun 29, 2025

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  • Analysis of accuracy, feasibility, cost-effectiveness, and technological advancements.
  • Evaluation of AI and deep learning applications in diagnostic interpretation.
  • Main Results:

    • OCT offers high accuracy and reproducibility but is limited by cost and portability.
    • Optic disc photography is accessible and cost-effective but suffers from subjective interpretation.
    • AI shows potential to improve optic disc photo analysis, especially when trained on objective OCT data.

    Conclusions:

    • Both OCT and optic disc photography are valuable for glaucoma screening but are not interchangeable.
    • AI integration, particularly with objective OCT data, may optimize large-scale glaucoma screening programs.
    • Addressing challenges like low positive predictive value (PPV) is essential for effective screening.