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Updated: Jun 29, 2025

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Published on: June 2, 2023
Primary squamous cell carcinoma of thyroid gland-First case report from state Punjab, India
Manjinder S Sidhu1, Davinder Paul2, Puneet Bhutani3
1Department of Radiation Oncology, DMCH Cancer Centre, Ludhiana, Punjab, India.
Abstract:
Primary squamous cell carcinoma of the thyroid is a very rare thyroid malignancy. In addition, due to its presentation as a locally advanced disease with a high tendency to metastasize, it has a poor prognosis and outcome. We report a 60-year-old male patient with PSCC, which was confirmed by immunohistochemistry on biopsy. The patient was staged as T4N1M0 and was planned as per the multidisciplinary team approach. In sum, pathologic examination and IHC aid in distinguishing this lesion and help in differentiating it from other tumors of similar histology. Furthermore, it also aids in planning treatment.
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