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Published on: August 11, 2015
15-Year Analysis of Surgical Approaches and Outcomes for Coarctation in 132 Neonates and Infants
Yuriy Stukov1, Jeffrey P Jacobs1, Omar M Sharaf1
1Congenital Heart Center, University of Florida, 1600 Archer Road, Gainesville, FL, 32608, USA.
Insights
This study shows that tailoring surgical methods to individual patient anatomy for aortic coarctation repair in infants results in low operative mortality and recurrence rates. Personalized surgical approaches for aortic coarctation in infants are safe and effective.
Area of Science:
- Pediatric Cardiac Surgery
- Congenital Heart Disease
- Aortic Arch Anomalies
Background:
- Surgical repair of aortic coarctation in neonates and infants has various approaches.
- An individualized strategy matching surgical technique to patient anatomy is employed.
Purpose of the Study:
- To evaluate operative characteristics and outcomes of surgical repair for aortic coarctation or hypoplastic aortic arch in infants.
- To assess outcomes based on surgical approach: Median Sternotomy vs. Left Lateral Thoracotomy.
- To analyze outcomes including operative mortality and recurrence rates.
Main Methods:
- Retrospective review of 132 infants (0-1 year) undergoing surgical repair of aortic coarctation or hypoplastic aortic arch from 2006-2021.
- Patients divided into Median Sternotomy (Group 1) and Left Lateral Thoracotomy (Group 2) groups.
- Analysis of operative techniques, mortality, and re-intervention rates.
Main Results:
- Operative mortality was 0.76% (1/132 patients).
- Recurrent coarctation requiring transcatheter intervention occurred in 5.3% (7/132).
- Surgical re-intervention for recurrent coarctation was needed in 2.3% (3/132).
Conclusions:
- An individualized surgical approach for aortic coarctation and hypoplastic aortic arch in infants is associated with low operative mortality (<1%).
- This strategy also demonstrates a low rate of recurrent coarctation requiring reoperation (<3%).
- Matching surgical approach to individual anatomy is effective for treating these complex pediatric cardiac conditions.
Abstract:
A variety of surgical approaches exist to treat aortic coarctation in neonates and infants. Our institutional approach is designed to match the surgical approach to the individual anatomy of the patient. The objective of this study is to evaluate operative characteristics and outcomes of all neonates and infants who underwent surgical repair of coarctation of the aorta or hypoplastic aortic arch at University of Florida from 2006 to 2021, inclusive, either in isolation or with concomitant repair of atrial septal defect (ASD) and/or ventricular septal defect (VSD). A retrospective review was performed of 132 patients aged 0-1 year who underwent surgical repair of aortic coarctation or hypoplastic aortic arch between 2006 and 2021, inclusive, either in isolation or with concomitant repair of ASD and/or VSD. Patients were divided into two groups based on the surgical approach: Group 1 = Median Sternotomy and Group 2 = Left Lateral Thoracotomy. Continuous variables are presented as median (minimum-maximum); categorical variables are presented as N (%). The most common operative technique in Group 1 was end-to-side reconstruction with ligation of the aortic isthmus. The most common operative technique in Group 2 was extended end-to-end repair. Operative Mortality was one patient (1/132 = 0.76%). Transcatheter intervention for recurrent coarctation was performed in seven patients (7/132 = 5.3%). Surgical re-intervention for recurrent coarctation was performed in three patients (3/132 = 2.3%). From these data, one can conclude that a strategy of matching the surgical approach to the anatomy of neonates and infants who underwent surgical repair of aortic coarctation or hypoplastic aortic arch, either in isolation or with concomitant repair of ASD and/or VSD, is associated with less than 1% Operative Mortality and less than 3% recurrent coarctation requiring reoperation.

