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Primary Calvarial Lymphoma: A Case Report.

Mohammad G Abdoh¹, Balgees Ajlan², Abdulaziz A Basurrah¹

¹Neurosurgery Department, King Abdullah Medical City, Makkah, SAU.

|April 1, 2024

Summary

Calvarial lymphoma, a rare skull tumor, mimics other conditions but requires prompt diagnosis. Biopsy and chemoradiation may be sufficient, avoiding extensive surgery for this rare entity.

Keywords:

b-cell biopsy calvarial lymphoma skull lesion

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Area of Science:

Oncology
Radiology
Pathology

Background:

Calvarial lymphoma is a rare condition that can be mistaken for other skull lesions like meningiomas or metastatic carcinomas.
Early detection and accurate diagnosis of calvarial lymphoma are crucial for effective patient management.

Observation:

A 45-year-old female presented with a progressively enlarging forehead swelling.
Initial workup, including metastatic survey and bone marrow biopsy, was negative.
A lesion initially considered for extensive resection was diagnosed as large B-cell lymphoma via biopsy.

Findings:

Primary calvarial lymphoma can present as a progressively growing skull lesion.
Radiological similarity to other tumors necessitates a high index of suspicion for calvarial lymphoma.

Implications:

Considering calvarial lymphoma in the differential diagnosis can prevent unnecessary extensive surgical resection.
A less invasive approach involving biopsy and chemoradiation may be the optimal management strategy for calvarial lymphoma.