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Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A
Rafael José Vieira1, Lucas Leemann2, Andrew Briggs3
1Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal; Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal.
Summary
Poor control of allergic rhinitis (AR) and asthma significantly reduces health-related quality of life. Mobile health data provide valuable insights into patient quality of life for AR and asthma management.
Area of Science:
- Allergy and Immunology
- Respiratory Medicine
- Health Outcomes Research
Background:
- Allergic rhinitis (AR) and asthma negatively impact health-related quality of life.
- National estimates for quality of life in patients with AR or asthma are limited.
Purpose of the Study:
- To estimate utility scores and EuroQoL five-dimension (EQ-5D) visual analog scale (VAS) for patients with AR or asthma.
- To assess the impact of disease control levels on quality of life.
Main Methods:
- Cross-sectional study utilizing patient data from the MASK-air app across Europe.
- Quality of life measured using the EQ-5D instrument (utility scores and EQ-5D VAS).
- Multilevel regression models with poststratification analyzed data, controlling for age and sex.
Main Results:
- Poor AR control associated with utilities from 0.72-0.85 and EQ-5D VAS from 55.3-64.2.
- Poor asthma control associated with utilities from 0.73-0.87 and EQ-5D VAS from 51.4-64.2.
- Poor disease control led to a mean utility loss of 0.14 for both conditions; combined AR and asthma showed lower quality of life.
Conclusions:
- Reduced quality of life is linked to poor control of AR and asthma.
- Mobile health data offer valuable insights for health technology assessment.
- Estimates provide a basis for understanding patient-reported outcomes in respiratory conditions.
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