Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evidence of Heartland and Bourbon Viruses Transmitted by Ticks in Suffolk County, New York.

The American journal of tropical medicine and hygiene·2026

Same author

Evolutionary history of Jamestown Canyon virus reveals complex multi-vector ecology.

Current biology : CB·2026

Same author

OspA antibodies inhibit the <i>in vitro</i> transmigration of <i>Borrelia burgdorferi</i>.

Infection and immunity·2026

Same author

Broadly conserved protective epitopes on the lyme disease vaccine antigen, OspA.

PLoS pathogens·2026

Same author

An Fc-silent OspA monoclonal antibody passively protects mice from tick and intradermal Borrelia burgdorferi challenge.

PloS one·2026

Same author

Maternal expression and breast milk transfer of an mRNA- encoded monoclonal antibody in a murine model of cholera.

PLoS neglected tropical diseases·2026

Search research articles

Related Experiment Video

Updated: Jun 29, 2025

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

Quantitating SARS-CoV-2 Neutralizing Antibodies from Human Dried Blood Spots.

Katherine Berman¹, Greta Van Slyke¹, Hayley Novak¹

¹Division of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY 12208.

Biorxiv : the Preprint Server for Biology

|April 2, 2024

Summary

Dried blood spots (DBS) can reliably measure neutralizing antibodies against SARS-CoV-2. This method enables functional antibody assessment in diverse populations, including vulnerable and hard-to-reach communities.

Keywords:

Antibody COVID-19 Human Neutralizing Serology

More Related Videos

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Published on: March 13, 2015

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

Related Experiment Videos

Last Updated: Jun 29, 2025

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Published on: March 13, 2015

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

Area of Science:

Immunology
Virology
Public Health

Background:

Dried blood spots (DBS) were crucial for early COVID-19 pandemic seroprevalence studies.
With high SARS-CoV-2 seropositivity, focus shifts to assessing functional antibodies using DBS.
Evaluating neutralizing antibodies in specific cohorts is now a key public health objective.

Conclusions:

Dried blood spots (DBS) are suitable for reliably measuring SARS-CoV-2 neutralizing antibodies.
This validates DBS as a valuable tool for functional antibody assessment in various populations.
DBS facilitates the study of vulnerable and hard-to-reach communities, expanding public health surveillance capabilities.