Can Radiological Tumour Thickness Predict Pathological Prognostic Factors in Clinicoradiologically Node-Negative Oral...

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Investigating correlations between radiological tumor thickness (rTT) from CT scans and pathological prognostic factors.
• Focusing on clinicoradiologically node-negative squamous cell carcinoma of the buccal mucosa.
• Examining pathological tumor thickness (pTT), depth of invasion (DOI), and cervical nodal metastasis.

Purpose of the Study:

• To determine if rTT on CT scans can predict pathological prognostic factors.
• To establish the relationship between rTT and pTT, DOI, and nodal status.
• To enhance prognostic accuracy for oral squamous cell carcinoma.

Main Methods:

• Correlation analysis of rTT from preoperative CT scans.
• Inclusion of 61 untreated, clinicoradiologically node-negative buccal mucosa squamous cell carcinoma patients.
• Comparison of rTT with pathological tumor thickness, DOI, and post-operative nodal metastasis.

Main Results:

• No statistically significant difference in mean rTT between patients with positive or negative post-operative nodal metastases.
• Significant correlations were found between rTT and other potential prognostic factors.
• Study included 61 patients (68.9% male, 31.1% female) with a median age of 54.

Conclusions:

• Preoperative CT scan tumor thickness (rTT) is a valuable predictor of post-operative prognostic factors.
• rTT can aid in risk stratification for oral squamous cell carcinoma.
• Further research can refine the use of radiological tumor thickness in treatment planning.