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Updated: Jun 29, 2025

Chemical Dimerization-Induced Protein Condensates on Telomeres
Published on: April 12, 2021
Phase-Separated Biomolecular Condensation in Cancer: New Horizons and Next Frontiers
Trever G Bivona1,2,3
1Department of Medicine, Division of Hematology/Oncology, University of California, San Francisco, California.
Summary:
Beyond lipid membrane compartments, cells including cancer cells utilize various membraneless compartments, often termed biomolecular condensates, to regulate or organize key cellular processes underlying physiologic or pathologic phenotypes. In this commentary, the emergence of biomolecular condensation in cancer biology is highlighted, with a focus on key unanswered questions and with implications for improving the understanding of cancer pathogenesis and developing innovative cancer management strategies.
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