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Updated: Jun 29, 2025

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Mass spectrometry for neurosurgery: Intraoperative support in decision-making
Stanislav I Pekov1,2,3, Denis S Bormotov2, Svetlana I Bocharova2
1Skolkovo Institute of Science and Technology, Moscow, Russian Federation.
None:
Ambient ionization mass spectrometry was proved to be a powerful tool for oncological surgery. Still, it remains a translational technique on the way from laboratory to clinic. Brain surgery is the most sensitive to resection accuracy field since the balance between completeness of resection and minimization of nerve fiber damage determines patient outcome and quality of life. In this review, we summarize efforts made to develop various intraoperative support techniques for oncological neurosurgery and discuss difficulties arising on the way to clinical implementation of mass spectrometry-guided brain surgery.
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