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Simultaneous brain and neck time-of-flight MRA using spiral multiband with localized quadratic encoding
Xi Peng1,2, Dinghui Wang1, Daniel Borup3
1Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Magnetic Resonance in Medicine
|April 5, 2024
Summary
This study introduces a fast magnetic resonance angiography (MRA) technique for simultaneous brain and neck imaging. The novel method significantly reduces scan time and venous signal contamination for clearer artery visualization.
Area of Science:
- Medical Imaging
- Radiology
- Neuroimaging
Background:
- Time-of-flight magnetic resonance angiography (ToF-MRA) is crucial for visualizing blood vessels.
- Simultaneous brain and neck MRA is challenging due to time constraints and potential signal interferences.
Purpose of the Study:
- To develop an efficient method for simultaneous brain and neck ToF-MRA.
- To achieve this within practical scan timeframes.
Main Methods:
- A spiral multiband (MB) localized quadratic (LQ) encoding method was proposed.
- Tilt-optimized non-saturated excitation (TONE) and partial-Fourier slice selection (PFSS) were integrated to reduce venous signal contamination.
- A sequential spiral MB and LQ reconstruction pipeline was utilized.
Main Results:
- Simultaneous brain and neck ToF-MRA was achieved in 2 minutes and 50 seconds.
- The MB and LQ acquisitions enhanced SNR-efficiency, allowing for greater spatial coverage without compromising scan time or SNR.
- TONE and PFSS effectively minimized venous contamination and improved sensitivity to small vessels.
Conclusions:
- A novel MB spiral LQ approach enables rapid intracranial and carotid ToF-MRA with reduced venous interference.
- This method shows significant promise for MRA applications requiring extensive spatial coverage.
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