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Updated: Jun 29, 2025
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
Published on: August 20, 2018
Synthesis, characterization and supra-molecular analysis for (E)-3-(pyridin-4-yl)acrylic acid
Valentina Florez-Muñoz1, Andres Felipe Guerrero1, Mario Macias2
1Facultad de Ciencias Básicas, Universidad Santiago de Cali, Calle 5 No 62-00, Cali, Colombia.
Abstract:
The title compound, C8H7NO2, crystallizes as prismatic colourless crystals in space group P , with one mol-ecule in the asymmetric unit. The pyridine ring is fused to acrylic acid, forming an almost planar structure with an E-configuration about the double bond with a torsion angle of -6.1 (2)°. In the crystal, strong O-H⋯N inter-actions link the mol-ecules, forming chains along the [101] direction. Weak C-H⋯O inter-actions link adjacent chains along the [100] direction, generating an R 2 2(14) homosynthon. Finally, π-π stacking inter-actions lead to the formation of the three-dimensional structure. The supra-molecular analysis was supported by Hirshfeld surface and two-dimensional fingerprint plot analysis, indicating that the most abundant contacts are associated with H⋯H, O⋯H/H⋯O, N⋯H/H⋯N and C⋯H/H⋯C inter-actions.
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