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Updated: Jun 29, 2025

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Pharmacological intestinal obstruction because of calcium polystyrene sulfonate administration
Benjamin Thorpe1, Salustiano Gonzalez Vinagre1, Daniel Santos2
1General Surgery Department, Hospital Clinico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Abstract:
Cation exchange resins are commonly used as treatment for hyperkalaemia in patients with chronic renal disease. There is a relation between cation exchange resins and the development of gastrointestinal adverse effects. A case of an intestinal obstruction at the terminal ileum is presented that underwent an ileocolic resection because of a critical stenosis of the intestine. The pathologist revealed abundant inflammatory cells together with deposits of calcium polystyrene crystals responsible of the intestinal obstruction. A rare cause of intestinal obstruction to bear in mind in chronically medicated patients with cation exchange resins.
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