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Exploring Head and Neck Paraganglioma: A Case Report.
Soumiya Samba1,2, Ahmed Bensghier1,2, Souad Margoum1,2
1Department of Radiation Oncology, Mohammed VI University Hospital, Oujda, MAR.
Cureus
|April 8, 2024
Summary
Paragangliomas (PGLs) are rare tumors originating from the autonomic nervous system. This case highlights an unusual head and neck PGL presentation in a 46-year-old female, successfully treated with radiotherapy.
Area of Science:
- Neuro-oncology
- Endocrinology
- Surgical Oncology
Background:
- Paragangliomas (PGLs) are rare neuroendocrine tumors arising from the autonomic nervous system.
- These tumors, similar to pheochromocytomas, originate from neural crest cells and can occur within or outside the adrenal glands.
- PGLs in the head and neck region are particularly uncommon.
Observation:
- A 46-year-old female presented with hypertension and persistent dysphonia, indicative of an unusual PGL manifestation.
- The patient's symptoms pointed towards a rare head and neck paraganglioma.
- Diagnostic evaluation confirmed the presence of a paraganglioma in the head and neck region.
Findings:
- The case report details the characteristics of a rare head and neck paraganglioma.
- Successful treatment was achieved through external radiotherapy.
- The patient's presentation underscores the diverse clinical manifestations of PGLs.
Implications:
- This case emphasizes the importance of considering PGLs in the differential diagnosis of head and neck masses, even with atypical symptoms.
- Raising awareness of rare PGL presentations can improve diagnostic accuracy and patient outcomes.
- Further research into the specific characteristics and treatment of head and neck paragangliomas is warranted.

