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Related Concept Videos

Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.

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Related Experiment Video

Updated: Jul 4, 2026

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Primary Spinal Marginal Zone Lymphoma Presenting With Spinal Cord Compression: A Case Report.

Mohammed Amine Guerrouaz1, Soufiane Berhili1, Mohamed Moukhlissi1

  • 1Department of Radiation Oncology, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Mohammed VI University Hospital, Oujda, MAR.

Cureus
|July 3, 2026
PubMed
Summary

Spinal extranodal marginal zone lymphoma (EMZL) is rare but can cause spinal cord compression. Surgical decompression and radiotherapy effectively treated a patient with this condition, leading to recovery.

Area of Science:

  • Hematology
  • Oncology
  • Neurosurgery
  • Radiation Oncology

Background:

Keywords:
malt lymphomamarginal zone lymphomaradiotherapyspinal compressionspinal lymphoma

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Last Updated: Jul 4, 2026

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  • Extranodal marginal zone lymphoma (EMZL) is an indolent B-cell neoplasm.
  • Spinal involvement by EMZL is exceptionally rare, often presenting as spinal cord compression.
  • This case highlights the diagnostic and therapeutic challenges of spinal EMZL.