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Updated: Jun 29, 2025

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Gastrointestinal radionuclide imaging in pediatric age group
Maria C Garganese1, Milena Pizzoferro2
1Nuclear Medicine Unit, Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy - mcarmen.garganese@opbg.net.
Insights
This review covers key pediatric gastrointestinal imaging techniques, including gastric emptying scintigraphy (GES), intestinal transit scintigraphy (ITS), and gastrointestinal bleeding scintigraphy, for diagnosing digestive disorders in children.
Area of Science:
- Pediatric Gastroenterology
- Medical Imaging
- Nuclear Medicine
Background:
- Digestive system disorders are common in children, requiring accurate diagnostic tools.
- Pediatric gastrointestinal imaging is essential for evaluating and managing these conditions.
- Functional imaging modalities offer non-invasive insights into gastrointestinal function.
Approach:
- This review details three scintigraphy techniques: gastric emptying scintigraphy (GES), intestinal transit scintigraphy (ITS), and gastrointestinal bleeding scintigraphy.
- It discusses protocols, clinical indications, and diagnostic capabilities of each modality.
- The role of SPECT-CT in improving accuracy and care standards is also highlighted.
Key Points:
- GES assesses stomach emptying for motility disorders, reflux, and abdominal pain.
- ITS, using Gallium-67, evaluates whole-gut transit for conditions like Hirschsprung disease.
- Gastrointestinal bleeding scintigraphy, using Technetium-99m, detects bleeding sources like Meckel's diverticulum.
Conclusions:
- These scintigraphy techniques are vital non-invasive tools in pediatric gastroenterology.
- They aid in diagnosing complex motility and bleeding disorders.
- Improved diagnostic accuracy leads to better surgical guidance and long-term outcomes.
Abstract:
Pediatric gastrointestinal imaging plays a crucial role in evaluating and managing digestive system disorders in children. This comprehensive review dives into the nuances of pediatric gastrointestinal imaging techniques, focusing on three specific modalities: gastric emptying scintigraphy (GES), intestinal transit scintigraphy (ITS), and gastrointestinal bleeding scintigraphy. GES involves real-time monitoring of stomach emptying using radiotracers and gamma camera technology. While challenges exist in standardizing protocols due to age-specific meal compositions, GES remains pivotal in diagnosing motility disorders, gastroesophageal reflux, and abdominal pain in children. ITS, utilizing [67Ga], provides insights into gastrointestinal motility disorders such as Hirschsprung disease. It aids in whole-gut transit evaluation, guiding surgical interventions and improving long-term clinical outcomes. Gastrointestinal bleeding scintigraphy, employing [99mTc], assists in diagnosing conditions like Meckel's diverticulum and occult bleeding, offering continuous monitoring to pinpoint the bleeding site along the entire gastrointestinal tract. SPECT-CT improves the accuracy and the standards of care. Each technique's protocol details, clinical indications, and diagnostic capabilities are thoroughly discussed, highlighting the importance of these non-invasive, functional imaging modalities in pediatric gastroenterology.
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