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Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
Published on: March 15, 2024
Aeromonas hydrophila induced necrotizing fasciitis following laparoscopic cholecystectomy
Taimoor Khalid Janjua1, Saba Siddique1, Mohammad Faisal Ibrahim1
1Department of General Surgery, Liaquat National Hospital and Medical College, Karachi, Pakistan.
Abstract:
Necrotizi ng fasciit is [NF] i s a m ultifaceted disease of the muscle fascia and body tissues which demands the earliest intervention. Past reviews have documented ver y few cases of Aeromonas Hydroph ila [AH] induced N F fol lo wing abdominal surgery. AH can cause fatal NF as seen in a 72 year old female patient reported at Liaquat National Hospital &Medical College; a ter tiary care center in Karachi, Pakistan on 2nd April, 2022. She had a k nown comorbidity of hypertension and presented with the chief complaint of symptomatic gallstones for which she unde rwent Laparoscopic Cholecystectomy (LAPCHOL). She developed NF of the lower ab domen post- oper atively. Following uneventful Laparoscopic Cholecystectomy our pati ent presented to the ER two days later with severe lower abdo minal pain and overlyi ng celluliti s. Fasc io to my revealed extensive myonecrosis with necrotizing soft tissue in fe ction. Despite u ndergoing extensive surgical debr idement and broad spectr um antibi ot ic administration; the patient died in the ICU on the fifth postoperat ive day followi ng septic complications. Histopathologica l an alysis, confirmed i nflammat ion and necrosis. Culture sensitivity of the debrided tissue revealed AH. Approach should lie towards analyzing the behaviour of such microbes in high risk patients through collective case studies. This is the first clinical case showcasing such parameters e ncountered in the General Surger y Department.
Insights
Necrotizing fasciitis is a severe infection. Aeromonas hydrophila caused fatal necrotizing fasciitis in a post-operative patient, highlighting the need for vigilance in high-risk individuals.
Area of Science:
- Infectious Diseases
- Surgical Pathology
- Microbiology
Background:
- Necrotizing fasciitis (NF) is a rapidly progressive soft tissue infection requiring prompt intervention.
- Aeromonas hydrophila (AH) is a rare but potent cause of NF, particularly following abdominal surgery.
- This case highlights a critical gap in understanding AH-induced NF in post-operative patients.
Observation:
- A 72-year-old female with hypertension developed severe lower abdominal pain and cellulitis post-Laparoscopic Cholecystectomy.
- Surgical exploration revealed extensive myonecrosis and necrotizing soft tissue infection.
- Histopathology confirmed inflammation and necrosis, with tissue cultures identifying Aeromonas hydrophila.
Findings:
- Aeromonas hydrophila was identified as the causative agent of necrotizing fasciitis in this patient.
- Despite aggressive surgical debridement and broad-spectrum antibiotics, the patient succumbed to septic complications.
- This case represents the first documented instance of AH-induced NF in the General Surgery Department of this tertiary care center.
Implications:
- Early recognition and intervention are crucial for managing Aeromonas hydrophila-induced necrotizing fasciitis.
- Further collective case studies are needed to analyze the behavior of AH in high-risk surgical patients.
- This case underscores the importance of considering rare pathogens in post-operative infections.
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