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Adult Ileoileal Intussusception Caused by Diffuse Large B-cell Lymphoma⋆
Scarlet Louis-Jean1, Shire Chaudhry1, Stephanie Richards1
1Internal Medicine Department, Luminis Health Anne Arundel Medical Center, Annapolis, MD, USA.
Journal of Community Hospital Internal Medicine Perspectives
|April 10, 2024
Summary
Adult intussusception can be a rare sign of diffuse large B-cell lymphoma (DLBCL). Early diagnosis and treatment, including surgery and R-CHOP chemotherapy, led to complete remission in a CD20-positive DLBCL patient.
Area of Science:
- Gastroenterology and Oncology
Background:
- Adult intussusception is uncommon, often presenting with vague symptoms.
- Malignancy is an infrequent but significant cause of adult intussusception.
Observation:
- A middle-aged male presented with non-specific intussusception symptoms and no classic B symptoms.
- Imaging revealed intussusception caused by a CD20-positive diffuse large B-cell lymphoma (DLBCL).
Findings:
- The patient had stage IIIE DLBCL leading to small bowel intussusception.
- Surgical resection followed by R-CHOP chemotherapy achieved complete remission.
Implications:
- Highlights the importance of considering malignancy in adult intussusception.
- Demonstrates the efficacy of combined surgical and chemotherapeutic management for DLBCL-induced intussusception.
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