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Efficient one-pot assembly of higher-order DNA nanostructures by chemically conjugated branched DNA

Raja Muhammad Aqib1,2, Yuang Wang1, Jianbing Liu1,2

  • 1CAS Key Laboratory of Nanosystem and Hierarchical Fabrication, National Center for Nanoscience and Technology, Beijing 100190, China. liujb@nanoctr.cn.

Chemical Communications (Cambridge, England)
|April 10, 2024
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DNA Packaging00:58

DNA Packaging

Overview
Nucleic Acid Structure01:25

Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA has a double-helix structure. The...