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Updated: Jun 28, 2025

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

Engineering Microorganisms for Cancer Immunotherapy.

Dingkang Liu¹, Lichao Yu¹, Haibo Rong²

¹Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing, 211198, China.

Advanced Healthcare Materials

|April 10, 2024

Summary

This summary is machine-generated.

Engineered microorganisms, including bacteria and viruses, are emerging as a powerful tool in cancer immunotherapy. These modified microbes can target cancer cells and enhance immune responses, offering new personalized treatment possibilities.

Keywords:

bacterial cancer immunotherapy engineering microorganisms virus

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Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics

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Published on: June 7, 2024

Area of Science:

Biotechnology
Immunology
Oncology

Background:

Cancer immunotherapy leverages the immune system to combat cancer.
Engineered microorganisms are a novel strategy in this field.
Synthetic biology and genetic engineering are key to developing these therapies.

Purpose of the Study:

To review microorganism-based therapies for cancer immunotherapy.
To explore strategies for enhancing treatment efficacy and safety.
To discuss ethical considerations in developing these novel treatments.

Main Methods:

Review of current literature on engineered microorganism-based cancer therapies.
Analysis of synthetic biology and genetic engineering techniques.
Examination of safety and ethical frameworks.

Main Results:

Engineered microorganisms show potential for targeted cancer treatment.
These therapies can modulate the immune system effectively.
Various strategies exist to improve efficacy and safety.

Conclusions:

Microorganism-based cancer immunotherapy is a rapidly advancing field.
Further research is needed to optimize efficacy, safety, and ethical guidelines.
These therapies hold promise for innovative, personalized cancer treatments.