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Multi-branch myocardial infarction detection and localization framework based on multi-instance learning and domain

Xinyue Li1, Yangcheng Huang1, Yixin Ning1

  • 1School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, People's Republic of China.

Physiological Measurement
|April 10, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces two models for detecting and localizing myocardial infarction (MI) using electrocardiograms (ECGs). The proposed methods show high accuracy, offering a promising tool for early cardiovascular disease diagnosis.

Keywords:
ECGattention mechanismdomain knowledgemultiple-instance learningmyocardial infarction

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Myocardial infarction (MI) causes irreversible heart damage, necessitating early detection.
  • Automatic MI detection and localization from electrocardiograms (ECGs) are challenging clinical problems.

Purpose of the Study:

  • To develop and evaluate novel deep learning models for accurate MI detection and localization.
  • To improve the precision of MI diagnosis using ECG data.

Main Methods:

  • Proposed two models: MFB-SENET for MI detection and MFB-DMIL for MI localization.
  • MFB-DMIL integrates multi-instance learning with domain knowledge, handcrafted features, and a novel 'lead-loss' function.
  • Utilized Grad-CAM for visualizing model decision-making processes.

Main Results:

  • On the PTB database, MI detection accuracy reached 93.88% and localization accuracy reached 67.17%.
  • On the PTB-XL database, MI detection accuracy was 94.89% and localization accuracy was 85.83%.
  • Performance was comparable or superior to existing state-of-the-art algorithms.

Conclusions:

  • The combined deep learning and domain knowledge approach is effective and reliable for MI diagnosis.
  • The proposed models show potential as efficient tools to aid physicians in diagnosing MI.
  • This work advances automated analysis of ECG for cardiovascular disease detection.