Effect of methylprednisolone on complications after removal of impacted mandibular third molars

Bilateral impacted mandibular third molars were surgically removed in 20 healthy patients. The effects of methylprednisolone on postoperative healing was investigated in a double-blind, cross-over study. Some decrease in postoperative discomfort (swelling and trismus) was noted in the methylprednisolone group. No statistically significant difference was noted, however in comparison with a placebo group.