Uptake of cadmium in developing rat teeth in organ culture

Molar teeth from 9-day-old rats were cultured for 7 days in medium supplemented with 1 or 10 ppm Cd for 1 or 3 h or 7 days. After culture the Cd concentrations were measured separately from the mineralizing parts and the cell-containing tissues. The accumulation of Cd increased with the duration of treatment and the concentration used, being more intensive in the hard parts than the soft tissues of the teeth.