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Vitamin D and Insulin-Dependent Diabetes: A Systematic Review of Clinical Trials
Yuval Dadon1, Lior Hecht Sagie1, Francis B Mimouni2,3
1Ministry of Health, Jerusalem 9101002, Israel.
Vitamin D supplementation does not show strong evidence for preserving beta-cells or improving glycemic control in new-onset type 1 diabetes mellitus (T1DM). Further research is needed, though adequate vitamin D is advised for bone health in T1DM patients.
Area of Science:
- Endocrinology
- Pediatrics
- Nutritional Science
Background:
- Conflicting results exist regarding vitamin D supplementation's effect on beta-cell preservation after type 1 diabetes mellitus (T1DM) onset.
- The role of vitamin D in managing new-onset T1DM requires further clarification.
Conclusions:
- More rigorous and larger studies are necessary to definitively assess vitamin D's impact on beta-cell function and glycemic control in new-onset T1DM.
- Adequate vitamin D levels are recommended for patients with new-onset T1DM due to the risk of osteopenia.
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