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Epistaxis

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...

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Related Experiment Video

Updated: Jun 28, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Epistaxis Rates and Health Care Utilization in Patients With a Ventricular Assist Device.

Eric Rohe¹, Sarah Schmoker¹, Kaeli Samson²

¹Department of Otolaryngology Head and Neck Surgery, College of Medicine University of Nebraska Medical Center Nebraska Nebraska USA.

|April 15, 2024

Summary

This summary is machine-generated.

Ventricular assist device (VAD) patients frequently experience nosebleeds (epistaxis), with nearly 30% requiring medical attention. Gastrointestinal bleeding and kidney disease increase the risk of epistaxis in VAD recipients.

Keywords:

epistaxis ventricular assist device

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Last Updated: Jun 28, 2025

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Published on: June 12, 2021

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Published on: August 16, 2021

Area of Science:

Cardiology
Medical Devices
Hematology

Background:

Ventricular assist device (VAD) implantation enhances survival and quality of life but is associated with significant bleeding complications.
Epistaxis is a common concern in VAD patients, necessitating an understanding of its incidence and associated risk factors.

Purpose of the Study:

To determine baseline rates of epistaxis in patients with VADs.
To analyze trends in healthcare utilization related to epistaxis within the VAD population.
To identify risk factors associated with epistaxis in VAD recipients.

Main Methods:

A retrospective cohort study was conducted involving a chart review of adult VAD patients at a single center.
Descriptive statistics were analyzed using appropriate statistical tests (χ², t-tests, Fisher's exact test).
Logistic regression modeling was employed to assess the association between epistaxis and other clinical variables.

Main Results:

Out of 290 VAD patients, 98 (33.8%) experienced epistaxis, and 84 (29.0%) sought medical attention.
Patients with a history of gastrointestinal (GI) bleeding showed higher rates of epistaxis (42.4% vs. 29.0%).
Logistic regression revealed that GI bleeding (adjusted odds ratio [aOR]: 1.94, 95% CI: 1.12-3.37) and kidney disease (aOR: 1.83, 95% CI: 1.06-3.13) were significantly associated with increased odds of epistaxis.

Conclusions:

Approximately 29% of VAD patients received medical care for epistaxis at this institution.
Gastrointestinal bleeding and kidney disease are identified as significant risk factors for epistaxis in the VAD population.
A substantial proportion of epistaxis events occurred during inpatient stays (59%) or in the emergency department (32.8%), suggesting a need for proactive management strategies.