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[Relation between COVID-19 and Guillain-Barré syndrome in adults. Systematic review]
L M Trujillo Gittermann1,2, S N Valenzuela Feris3, A von Oetinger Giacoman4,5
1Escuela de Kinesiología, Facultad de Ciencias de la Salud, Universidad de las Américas, Santiago, Chile.
Neurologia (Barcelona, Spain)
|April 15, 2024
Summary
A strong association exists between COVID-19 and Guillain-Barré syndrome (GBS). This review found that COVID-19-associated GBS cases often present with more severe symptoms.
Area of Science:
- Neurology
- Infectious Diseases
- Epidemiology
Context:
- Growing number of reported cases linking COVID-19 infection with Guillain-Barré syndrome (GBS).
- Limited comprehensive understanding of the clinical implications and presentation of this association in adults.
Purpose:
- To systematically review and analyze existing evidence on the association between COVID-19 and Guillain-Barré syndrome in the adult population.
- To elucidate the characteristics and severity of GBS in the context of SARS-CoV-2 infection.
Summary:
- A systematic review of 47 identified studies, with final analysis of 24 articles involving 30 patients, was conducted.
- The review identified a significant association between COVID-19 and Guillain-Barré syndrome.
- Findings indicate that COVID-19-associated GBS may present with increased symptom severity compared to non-COVID-19 related GBS.
Impact:
- Provides crucial insights into the neurological complications of COVID-19.
- Highlights the need for increased clinical vigilance for GBS in COVID-19 patients.
- Informs diagnostic and management strategies for patients presenting with GBS during the pandemic.
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